diff --git a/homeassistant/util/package.py b/homeassistant/util/package.py
index 9720bbd4ca3..2c0ed363eef 100644
--- a/homeassistant/util/package.py
+++ b/homeassistant/util/package.py
@@ -86,6 +86,10 @@ def is_installed(requirement_str: str) -> bool:
                 "Installed version for %s resolved to None", req.name
             )
             return False
+        if req.url:
+            # If requirement is a URL, we cannot verify versions, so let
+            # the package manager handle it
+            return False
         return req.specifier.contains(installed_version, prereleases=True)
     except PackageNotFoundError:
         return False
diff --git a/tests/util/test_package.py b/tests/util/test_package.py
index e3635dd2bea..67e4ade09b2 100644
--- a/tests/util/test_package.py
+++ b/tests/util/test_package.py
@@ -400,6 +400,11 @@ def test_get_is_installed() -> None:
     assert package.is_installed(f"{installed_package}<={installed_version}")
     assert not package.is_installed(f"{installed_package}<{installed_version}")
 
+    # URL-based requirements should always return False, as no version check is possible
+    assert not package.is_installed(
+        "homeassistant@git+https://github.com/home-assistant/core.git@dev"
+    )
+
 
 def test_check_package_previous_failed_install() -> None:
     """Test for when a previously install package failed and left cruft behind."""