diff --git a/homeassistant/components/telegram_bot/bot.py b/homeassistant/components/telegram_bot/bot.py
index a0f7cc841a2..d1ab9e62b24 100644
--- a/homeassistant/components/telegram_bot/bot.py
+++ b/homeassistant/components/telegram_bot/bot.py
@@ -108,8 +108,8 @@ from .const import (
     SERVICE_SEND_STICKER,
     SERVICE_SEND_VIDEO,
     SERVICE_SEND_VOICE,
-    SIGNAL_UPDATE_EVENT,
 )
+from .helpers import signal
 
 _FILE_TYPES = ("animation", "document", "photo", "sticker", "video", "voice")
 _LOGGER = logging.getLogger(__name__)
@@ -169,7 +169,7 @@ class BaseTelegramBot:
 
         _LOGGER.debug("Firing event %s: %s", event_type, event_data)
         self.hass.bus.async_fire(event_type, event_data, context=event_context)
-        async_dispatcher_send(self.hass, SIGNAL_UPDATE_EVENT, event_type, event_data)
+        async_dispatcher_send(self.hass, signal(self._bot), event_type, event_data)
         return True
 
     @staticmethod
@@ -551,7 +551,7 @@ class TelegramNotificationService:
                     EVENT_TELEGRAM_SENT, event_data, context=context
                 )
                 async_dispatcher_send(
-                    self.hass, SIGNAL_UPDATE_EVENT, EVENT_TELEGRAM_SENT, event_data
+                    self.hass, signal(self.bot), EVENT_TELEGRAM_SENT, event_data
                 )
         except TelegramError as exc:
             if not suppress_error:
diff --git a/homeassistant/components/telegram_bot/event.py b/homeassistant/components/telegram_bot/event.py
index db45c4c135a..04e8ecb8246 100644
--- a/homeassistant/components/telegram_bot/event.py
+++ b/homeassistant/components/telegram_bot/event.py
@@ -14,9 +14,9 @@ from .const import (
     EVENT_TELEGRAM_COMMAND,
     EVENT_TELEGRAM_SENT,
     EVENT_TELEGRAM_TEXT,
-    SIGNAL_UPDATE_EVENT,
 )
 from .entity import TelegramBotEntity
+from .helpers import signal
 
 
 async def async_setup_entry(
@@ -55,7 +55,7 @@ class TelegramBotEventEntity(TelegramBotEntity, EventEntity):
         self.async_on_remove(
             async_dispatcher_connect(
                 self.hass,
-                SIGNAL_UPDATE_EVENT,
+                signal(self.config_entry.runtime_data.bot),
                 self._async_handle_event,
             )
         )
diff --git a/homeassistant/components/telegram_bot/helpers.py b/homeassistant/components/telegram_bot/helpers.py
new file mode 100644
index 00000000000..4b4acbb37fa
--- /dev/null
+++ b/homeassistant/components/telegram_bot/helpers.py
@@ -0,0 +1,10 @@
+"""Helper functions for Telegram bot integration."""
+
+from telegram import Bot
+
+from .const import SIGNAL_UPDATE_EVENT
+
+
+def signal(bot: Bot) -> str:
+    """Define signal name."""
+    return f"{SIGNAL_UPDATE_EVENT}_{bot.id}"
diff --git a/tests/components/telegram_bot/test_event.py b/tests/components/telegram_bot/test_event.py
index e1e1cff68eb..70d3c6960dc 100644
--- a/tests/components/telegram_bot/test_event.py
+++ b/tests/components/telegram_bot/test_event.py
@@ -37,4 +37,5 @@ async def test_send_message(
     await hass.async_block_till_done()
 
     state = hass.states.get("event.mock_title_update_event")
+    assert state is not None
     assert state.attributes == snapshot(exclude=props("config_entry_id"))