diff --git a/Dockerfile b/Dockerfile
index 55df84e84538..a64cb7c82768 100644
--- a/Dockerfile
+++ b/Dockerfile
@@ -30,7 +30,7 @@ RUN \
     # Verify go2rtc can be executed
     go2rtc --version \
     # Install uv
-    && pip3 install uv==0.9.26
+    && pip3 install uv==0.10.6
 
 WORKDIR /usr/src
 
diff --git a/homeassistant/package_constraints.txt b/homeassistant/package_constraints.txt
index 4b88531d33f2..e06b0866c622 100644
--- a/homeassistant/package_constraints.txt
+++ b/homeassistant/package_constraints.txt
@@ -71,7 +71,7 @@ standard-telnetlib==3.13.0
 typing-extensions>=4.15.0,<5.0
 ulid-transform==1.5.2
 urllib3>=2.0
-uv==0.9.26
+uv==0.10.6
 voluptuous-openapi==0.2.0
 voluptuous-serialize==2.7.0
 voluptuous==0.15.2
diff --git a/pyproject.toml b/pyproject.toml
index bd0837031bf8..51f3123e5e0a 100644
--- a/pyproject.toml
+++ b/pyproject.toml
@@ -78,7 +78,7 @@ dependencies = [
   "typing-extensions>=4.15.0,<5.0",
   "ulid-transform==1.5.2",
   "urllib3>=2.0",
-  "uv==0.9.26",
+  "uv==0.10.6",
   "voluptuous==0.15.2",
   "voluptuous-serialize==2.7.0",
   "voluptuous-openapi==0.2.0",
diff --git a/requirements.txt b/requirements.txt
index 9491c8727390..d9ce90d32915 100644
--- a/requirements.txt
+++ b/requirements.txt
@@ -54,7 +54,7 @@ standard-telnetlib==3.13.0
 typing-extensions>=4.15.0,<5.0
 ulid-transform==1.5.2
 urllib3>=2.0
-uv==0.9.26
+uv==0.10.6
 voluptuous-openapi==0.2.0
 voluptuous-serialize==2.7.0
 voluptuous==0.15.2
diff --git a/script/hassfest/docker/Dockerfile b/script/hassfest/docker/Dockerfile
index 00b6128ef307..5935894994a8 100644
--- a/script/hassfest/docker/Dockerfile
+++ b/script/hassfest/docker/Dockerfile
@@ -14,7 +14,7 @@ WORKDIR "/github/workspace"
 COPY . /usr/src/homeassistant
 
 # Uv is only needed during build
-RUN --mount=from=ghcr.io/astral-sh/uv:0.9.26,source=/uv,target=/bin/uv \
+RUN --mount=from=ghcr.io/astral-sh/uv:0.10.6,source=/uv,target=/bin/uv \
     # Uv creates a lock file in /tmp
     --mount=type=tmpfs,target=/tmp \
     # Required for PyTurboJPEG