diff --git a/homeassistant/package_constraints.txt b/homeassistant/package_constraints.txt
index f65ea662d5f..40ec4f69444 100644
--- a/homeassistant/package_constraints.txt
+++ b/homeassistant/package_constraints.txt
@@ -90,9 +90,9 @@ httplib2>=0.19.0
 # gRPC is an implicit dependency that we want to make explicit so we manage
 # upgrades intentionally. It is a large package to build from source and we
 # want to ensure we have wheels built.
-grpcio==1.75.1
-grpcio-status==1.75.1
-grpcio-reflection==1.75.1
+grpcio==1.78.0
+grpcio-status==1.78.0
+grpcio-reflection==1.78.0
 
 # This is a old unmaintained library and is replaced with pycryptodome
 pycrypto==1000000000.0.0
diff --git a/script/gen_requirements_all.py b/script/gen_requirements_all.py
index 375716b6d71..73b319878f2 100755
--- a/script/gen_requirements_all.py
+++ b/script/gen_requirements_all.py
@@ -79,9 +79,9 @@ httplib2>=0.19.0
 # gRPC is an implicit dependency that we want to make explicit so we manage
 # upgrades intentionally. It is a large package to build from source and we
 # want to ensure we have wheels built.
-grpcio==1.75.1
-grpcio-status==1.75.1
-grpcio-reflection==1.75.1
+grpcio==1.78.0
+grpcio-status==1.78.0
+grpcio-reflection==1.78.0
 
 # This is a old unmaintained library and is replaced with pycryptodome
 pycrypto==1000000000.0.0