diff --git a/extensions/typescript-language-features/package.json b/extensions/typescript-language-features/package.json
index bd15126b55d..e3b7eadb0c4 100644
--- a/extensions/typescript-language-features/package.json
+++ b/extensions/typescript-language-features/package.json
@@ -983,6 +983,22 @@
           "markdownDescription": "%typescript.preferences.includePackageJsonAutoImports%",
           "scope": "window"
         },
+        "typescript.preferences.autoImportFileExcludePatterns": {
+          "type": "array",
+          "items": {
+            "type": "string"
+          },
+          "markdownDescription": "%typescript.preferences.autoImportFileExcludePatterns%",
+          "scope": "resource"
+        },
+        "javascript.preferences.autoImportFileExcludePatterns": {
+          "type": "array",
+          "items": {
+            "type": "string"
+          },
+          "markdownDescription": "%typescript.preferences.autoImportFileExcludePatterns%",
+          "scope": "resource"
+        },
         "javascript.preferences.renameShorthandProperties": {
           "type": "boolean",
           "default": true,
diff --git a/extensions/typescript-language-features/package.nls.json b/extensions/typescript-language-features/package.nls.json
index 513bcfbaaa1..03752b1f095 100644
--- a/extensions/typescript-language-features/package.nls.json
+++ b/extensions/typescript-language-features/package.nls.json
@@ -136,6 +136,7 @@
 	"typescript.preferences.includePackageJsonAutoImports.auto": "Search dependencies based on estimated performance impact.",
 	"typescript.preferences.includePackageJsonAutoImports.on": "Always search dependencies.",
 	"typescript.preferences.includePackageJsonAutoImports.off": "Never search dependencies.",
+	"typescript.preferences.autoImportFileExcludePatterns": "Specify glob patterns of files to exclude from auto imports. Requires using TypeScript 4.8 or newer in the workspace.",
 	"typescript.updateImportsOnFileMove.enabled": "Enable/disable automatic updating of import paths when you rename or move a file in VS Code.",
 	"typescript.updateImportsOnFileMove.enabled.prompt": "Prompt on each rename.",
 	"typescript.updateImportsOnFileMove.enabled.always": "Always update paths automatically.",
diff --git a/extensions/typescript-language-features/src/languageFeatures/fileConfigurationManager.ts b/extensions/typescript-language-features/src/languageFeatures/fileConfigurationManager.ts
index bc0ac10388b..caeb91d1dc3 100644
--- a/extensions/typescript-language-features/src/languageFeatures/fileConfigurationManager.ts
+++ b/extensions/typescript-language-features/src/languageFeatures/fileConfigurationManager.ts
@@ -3,6 +3,7 @@
  *  Licensed under the MIT License. See License.txt in the project root for license information.
  *--------------------------------------------------------------------------------------------*/
 
+import * as path from 'path';
 import * as vscode from 'vscode';
 import type * as Proto from '../protocol';
 import { ITypeScriptServiceClient } from '../typescriptService';
@@ -189,6 +190,8 @@ export default class FileConfigurationManager extends Disposable {
 			includeCompletionsWithSnippetText: config.get<boolean>('suggest.includeCompletionsWithSnippetText', true),
 			includeCompletionsWithClassMemberSnippets: config.get<boolean>('suggest.classMemberSnippets.enabled', true),
 			includeCompletionsWithObjectLiteralMethodSnippets: config.get<boolean>('suggest.objectLiteralMethodSnippets.enabled', true),
+			// @ts-expect-error until TS 4.8
+			autoImportFileExcludePatterns: this.getAutoImportFileExcludePatternsPreference(preferencesConfig, vscode.workspace.getWorkspaceFolder(document.uri)?.uri),
 			useLabelDetailsInCompletionEntries: true,
 			allowIncompleteCompletions: true,
 			displayPartsForJSDoc: true,
@@ -205,6 +208,18 @@ export default class FileConfigurationManager extends Disposable {
 			default: return this.client.apiVersion.gte(API.v333) ? 'auto' : undefined;
 		}
 	}
+
+	private getAutoImportFileExcludePatternsPreference(config: vscode.WorkspaceConfiguration, workspaceFolder: vscode.Uri | undefined): string[] | undefined {
+		return workspaceFolder && config.get<string[]>('autoImportFileExcludePatterns')?.map(p => {
+			// Normalization rules: https://github.com/microsoft/TypeScript/pull/49578
+			const slashNormalized = p.replace(/\\/g, '/');
+			const isRelative = /^\.\.?($|\/)/.test(slashNormalized);
+			return path.isAbsolute(p) ? p :
+				p.startsWith('*') ? '/' + slashNormalized :
+					isRelative ? vscode.Uri.joinPath(workspaceFolder, p).fsPath :
+						'/**/' + slashNormalized;
+		});
+	}
 }
 
 export class InlayHintSettingNames {